Best Varicose Veins Treatment in Jaipur
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Varicose veins are enlarged veins near the skin’s surface, often found in the legs due to increased pressure from standing and walking. For Best Varicose Veins Treatment in Jaipur, Dr. Manish Rajput provides advanced, personalized care using modern techniques to help you achieve healthier, smoother legs and a better quality of life.
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If you’re searching for the Best DVT Doctor in Jaipur, Dr. Manish Rajput stands out for his exceptional expertise and patient-focused care. Deep Vein Thrombosis (DVT) is a serious condition where blood clots form in the deep veins, often in the legs, potentially leading to life-threatening complications like pulmonary embolism. Dr. Manish Rajput is highly regarded for his advanced understanding of vascular conditions and his ability to provide precise, individualized treatment. Whether it’s medical management through anticoagulant therapy, minimally invasive procedures like thrombolysis, or venous stenting, he offers comprehensive solutions tailored to each patient’s needs. Dr. Manish stays updated with the latest advancements in diagnostic and therapeutic techniques, ensuring care of the highest international standards. Patients trust his compassionate approach, which emphasizes clear communication, thorough assessment, and long-term management strategies to prevent recurrence.
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Alarms for oxygen failure, low pressure, or high airway pressure.
Oxygen flush system for emergencies.
Hypoxic guard to prevent delivery of pure nitrous oxide (ensuring oxygen is always mixed i
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...
Regulatory Framework for Drug Import Under the Drugs and Cosmetics Act, 1940 ...Dr.Navaneethakrishnan S This presentation provides an in-depth overview of drug import regulations under the Drugs and Cosmetics Act, 1940, and its Rules, 1945. It covers key topics such as prohibited imports, import of new drugs, personal use import regulations, import licensing requirements, and storage conditions for scheduled drugs. It also explains government restrictions, exemptions, and penalties for violations. This guide is essential for pharmacy students, regulatory professionals, and individuals involved in the import and distribution of pharmaceutical products in India.
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PRETERM LABOR.pptx FOR NURSING STUDENTS CREATED BY KIRAN KARETHAKIRAN KARETHA PREMATURE LABOUR/ PRETERM LABOUR
DEFINITION:
Pre term labour is defined by WHO as onset of labour prior to the completion of 37 weeks of gestation in a pregnancy beyond 20 weeks of gestation.
INCIDENCE:
Globally, approximately 1 in 10 babies are born preterm (before 37 completed weeks of gestation), with an estimated 13.4 million preterm births annually. This means the incidence of preterm birth is roughly 10-11% worldwide.
In India, about 12% of babies are born preterm, which is higher than neighboring countries.
ETIOLOGY:
In about 50%, the cause of preterm labour is not known- IDIOPATHIC
Some of the high-risk factors are:
HISTORY: previous history of abortion or preterm delivery
Recurrent UTI
Smoking habits
Low socio-economic & nutritional status
Previous abortion history
Malpresentation
COMPLICATIONS IN PRESENT PREGNANCY: it may be due to maternal, fetal and placental.
SIGN AND SYMPTOMS:
Backache
Contractions every 10 minutes, are more often
Cramping in lower abdomen
Menstrual like cramps
Fluid leaking from vagina
Flu like symptoms
Increased pressure in pelvis
Increased vaginal bleeding
Regular uterine activity
Vaginal spotting
DIAGNOSIS:
Regular uterine contractions with or without pain (at least one in every 10 minutes.)
Dilation (2 cm or more) & effacement (80%) of the cervix
Length of cervix (2.5 cm or more.)
Funneling of internal OS
INVESTIGATIONS:
Blood test
Urine analysis, urine culture and sensitivity
Cervicovaginal swab: culture and fibronectin test
Serum electrolyte and glucose level
USG
COMPLICATION:
Birth of a pre-term baby
A pre-term baby usually has following problems:
• Low birth weight
• Birth asphyxia
• Neonatal jaundice
• Underdeveloped organs etc.
PREVENTIVE MEASURES:
However, it is not possible to prevent occurrence of preterm labour completely, though its prevalence can be reduced using various measures at following three levels-
1) Prevention at primary level
2) Prevention at secondary level
3) Prevention at tertiary level
1) Prevention at primary level
In this, actions are taken prior to the onset of any disease which reduce or remove the possibility for occurring a disease.
For preventing preterm labour, following measures are applied at primary level.
• Encourage the pregnant, to visit antenatal clinic regularly.
• To identify high risk factors at its incipient stage and to provide appropriate treatment accordingly.
• To provide special care to the women who have history of previous spontaneous abortion or preterm labour.
• Advice the pregnant women regarding:
Not to smoke and use of alcohol
To take well balanced diet
Avoid hard work
Iron folic acid supplementation
Maintaining adequate personal and environmental hygiene
To contact the doctor immediately if any abnormal symptoms arise
2) Prevention at secondary level
In this level, actions are taken at the incipient stage of the disease so that it can be diagnosed.
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Modern hyphenated techniques used in determination of adulteration of herbal drugs which includes TLC, HPTLC, HPLC, LC-MS, LC-NMR, SFC, LC-IR,etc.
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Principles of GALP
The fundamental principles of GALP include:
1. Data Integrity: Ensuring accurate, reliable, and tamper-proof data recording and analysis.
2. Regulatory Compliance: Adhering to national and international standards such as ISO, 21 CFR Part 11, and QCI guidelines.
3. Standardized Processes: Implementing well-defined SOPs to guide laboratory operations.
4. System Validation: Regularly verifying automated instruments and software for functionality and compliance.
5. Personnel Training: Ensuring that laboratory staff are adequately trained to operate automated systems efficiently and accurately.
6. Risk Management: Identifying and mitigating potential risks in automated workflows.
7. Continuous Improvement: Periodic reviews and updates to laboratory practices to incorporate technological advancements.
GALP Requirements
To implement GALP, laboratories must adhere to certain requirements:
1. Standardized Documentation: Maintaining comprehensive records of laboratory procedures and automation processes.
2. Software and Instrument Validation: Ensuring that all automated systems function as intended and comply with regulatory requirements.
3. Data Security Measures: Implementing encryption, access control, and audit trails for secure data management.
4. Regulatory Compliance: Aligning with relevant regulations such as 21 CFR Part 11, ISO standards, and QCI guidelines.
5. Personnel Competency: Conducting periodic training and assessments for laboratory staff.
6. Audit Readiness: Preparing for internal and external inspections by maintaining up-to-date documentation.
SOPs of GALP
Standard Operating Procedures (SOPs) form the backbone of GALP. These SOPs cover:
1. Instrument Calibration: Regular calibration and validation of automated instruments.
2. Data Entry and Management: Guidelines on recording, storing, and retrieving data in compliance with regulatory standards.
3. Sample Handling: Ensuring standardized procedures for sample collection, processing, and storage.
4. Software Usage and Maintenance: Guidelines on software validation, updates, and troubleshooting.
5. Audit Trail Management: Recording and reviewing all modifications made to electronic data.
6. Corrective and Preventive Actions (CAPA): Addressing non-compliance and implementing necessary improvements.
Training Documentation
A key aspect of GALP is personnel training, which includes:
1. Training Plans
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Honesty emphasizes transparency and truthfulness in communication and actions, fostering trust among colleagues, clients, and stakeholders.
Responsibility focuses on taking ownership of one’s actions and their consequences, fulfilling commitments, and being accountable for decisions made in a professional context.
Together, these qualities promote a positive work environment, enhance relationships, and contribute to long-term success and respect in any profession.
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Presented by: Dr. Faiza Ikram
Assistant Professor of Physiology
CMH Multan Institute of Medical Sciences
Qualifications: MBBS, FCPS (Physiology), ICMT, CHPE, DHPE, MPH, MBA
This meticulously crafted presentation on Red Blood Cell (RBC) Indices is part of a foundational series in physiology, focusing on the quantitative and qualitative analysis of red blood cells—a cornerstone in understanding anemias and various hematological disorders.
👩⚕️ Who Should Attend/View This Lecture?
This lecture is designed to cater to a wide academic and clinical audience:
💉 First and Second-Year MBBS students
🔬 Allied health sciences students (Nursing, DPT, MLS, etc.)
🩺 Interns and medical residents revising clinical hematology
📚 Medical educators preparing instructional content
🧫 Lab professionals and technologists refining interpretation skills
🧠 Postgraduate students in Physiology or Pathology
📘 Topics Covered in This Lecture Slide Deck:
RBC Count – Normal ranges for adults and neonates
Hemoglobin (Hb) – Clinical importance in oxygen transport
Packed Cell Volume (PCV) – Significance in hematocrit analysis
MCV (Mean Corpuscular Volume) – Cell sizing & anemia classification
MCH (Mean Corpuscular Hemoglobin) – Hemoglobin mass per RBC
MCHC (Mean Corpuscular Hemoglobin Concentration) – Indicator of chromicity
Color Index (CI) – Traditional but insightful ratio-based tool
RDW (Red Cell Distribution Width) – Variability in cell size and clinical implications
Osmotic Fragility – A functional test for membrane integrity and deformability
💡 What Makes This Lecture Unique?
✅ Simple and focused definitions with clinical relevance
✅ Step-by-step calculations using real-world examples
✅ Interpretive insights for differential diagnosis
✅ Color-coded cues and visually intuitive slides
✅ Bonus learning tips for quick recall and exam preparation
🎓 Whether you're preparing for a professional exam, clarifying core concepts, or refining your teaching tools—this SlideShare resource serves as an essential visual companion in your academic journey.
📩 Stay tuned for more lectures in this series!
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ECG-Interpretation-and-Management-of-Arrhythmias.pptx Dr ankush goyalDr Ankush goyal ECG Interpretation and Management
Introduction
Electrocardiography (ECG) is a crucial diagnostic tool used to assess the electrical activity of the heart. It provides essential information about heart rate, rhythm, conduction abnormalities, myocardial ischemia, and electrolyte disturbances. Correct interpretation of an ECG requires a systematic approach and understanding of normal and pathological waveforms.
Basics of ECG Interpretation
1. ECG Waves and Intervals
P wave: Represents atrial depolarization.
PR interval: Time from atrial depolarization to ventricular depolarization (normal: 120-200 ms).
QRS complex: Ventricular depolarization (normal: <120 ms).
ST segment: Represents the interval between ventricular depolarization and repolarization.
T wave: Represents ventricular repolarization.
QT interval: Duration of ventricular depolarization and repolarization (normal: <450 ms in males, <460 ms in females).
2. Systematic Approach to ECG Interpretation
1. Determine heart rate
Regular rhythm: 300 divided by the number of large squares between R waves.
Irregular rhythm: Count QRS complexes in 6 seconds and multiply by 10.
2. Assess heart rhythm
Regular or irregular?
Presence of P waves?
Relationship between P waves and QRS complexes?
3. Evaluate cardiac axis
Normal: -30 to +90 degrees.
Left axis deviation: <-30 degrees (e.g., left anterior hemiblock, left ventricular hypertrophy).
Right axis deviation: >+90 degrees (e.g., right ventricular hypertrophy, pulmonary embolism).
4. Analyze P wave morphology
Peaked P waves (right atrial enlargement).
Broad P waves (left atrial enlargement).
5. Assess PR interval
Short PR: Wolff-Parkinson-White syndrome.
Prolonged PR: First-degree AV block.
6. Inspect QRS complex
Narrow QRS (<120 ms): Normal conduction.
Wide QRS (>120 ms): Bundle branch block or ventricular origin.
7. Evaluate ST segment and T waves
ST elevation: Myocardial infarction.
ST depression: Ischemia or hypokalemia.
Inverted T waves: Ischemia, infarction, or hypertrophy.
8. Check QT interval
Prolonged QT: Risk of Torsades de Pointes.
Short QT: Hypercalcemia.
Common ECG Abnormalities and Management
1. Arrhythmias
a) Sinus Bradycardia
ECG Findings: HR < 60 bpm, normal P waves, and QRS complexes.
Causes: Increased vagal tone, hypothyroidism, beta-blockers.
Management: Treat underlying cause; consider atropine if symptomatic.
b) Sinus Tachycardia
ECG Findings: HR > 100 bpm, normal P waves, and QRS complexes.
Causes: Fever, dehydration, anemia, hyperthyroidism.
Management: Address underlying cause; beta-blockers if needed.
c) Atrial Fibrillation
ECG Findings: Irregularly irregular rhythm, absent P waves, fibrillatory waves.
Causes: Hypertension, valvular heart disease, hyperthyroidism.
Management: Rate control (beta-blockers, calcium channel blockers), rhythm control (amiodarone, cardioversion), anticoagulation (warfarin, DOACs).
d) Atrial Flutter
ECG Findings: Sawtooth flutter
Drug_Design PRESENTSTION B.pharm 6th sem. IGNTU AMARKANTAK M.P.
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rise and fall of ranitidine:- drug discovery pipeline
NDMA Contamination: A Ticking Time Bomb
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Claims by VALISURA
Testing Methods for NDMA
Regulatory Procedure Timeline
European Medical Agency
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usfda
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what are recalls
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(FDA recall, EMA recommendations)
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Additionally, this presentation focuses on the role of physiotherapy in managing RA. It covers various physiotherapy techniques, including exercise therapy, manual therapy, and modalities such as heat/cold therapy and TENS, which help improve joint mobility, reduce pain, and enhance overall function. It also emphasizes the importance of patient education and the need for a multidisciplinary approach to effectively manage RA.
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